Computational Biology Intitiatve
Location: Countway Library Harvard Medical School 10 Shattuck Street Boston, MA 02115
| Core Summary: |
In order to understand complexity of the central nervous system (CNS) as well as the genetic bases of nervous system disorders in humans it is necessary to detect and quantify the molecular changes that distinguish our brain from that our ancestors. The key differences may be at many levels of molecular organization, various stages of development, and at various points in the evolutionary history of life. To our benefit, data from these numerous levels of granularity and time are increasingly available either via experimental or computational means. If combined, these data should prove tremendously powerful for addressing fundamental questions about human cognition and neurological disease. The Computational Biology Lab was formed to take the lead in addressing these challenges, in particular by meeting the following chief aims:
(1) To provide a full comprehension of the molecular components essential to the development of the central nervous system in humans, and (2) To provide a complete description of these components within the context of human neurological disease and disorder.
| Categories and Institutions: |
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| Services: |
- Autworks
A web-driven navigation system that allows any researcher to view and search through the network of genes implicated in ASD and related neurological disorders
- BULL
A parallel BLAST service
- RoundUp
A large-scale database of orthology covering over 250 publicly available genomes
| Getting Started: |
We welcome your questions and comments via email
| Departmental Web Link: |