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HSCI iPS Cell Core Facility

Director: Rossi, Derrick J., Ph.D.; Cowan, Chad A., Ph.D.

Location: Harvard University, Bauer Building Room B01, 7 Divinity Avenue, Cambridge, MA 02138

Core Summary:

The HSCI iPS Core facility was created to accelerate research in the stem cell field by facilitating the derivation and distribution of iPS cell lines. Disease-specific iPS lines provide us with a unique opportunity to study the mechanisms of disease and ultimately to develop new treatments. The iPS Core serves as a repository for iPS cells produced by HSCI scientists and functions as a laboratory to produce disease-specific lines for sharing with the HSCI and broader research community.

Institutions:
  • Harvard Stem Cell Institute
Personnel/Contact Information:

Director: Rossi, Derrick J., Ph.D.
Phone: (617) 713-8900
Email

Director: Cowan, Chad A., Ph.D.
Phone: (617) 496-5222
Email

Member: Daheron, Laurence
Role: HSCI iPS Core Facility Manager
Phone: (617) 496-8059
Email

Member: General Inquiries
Email

Services:
  • Genome Editing of stem cells

    -In 2013, a new service was launched, offering the generation of genome engineered hESC or hiPS lines. We currently offer TALEN or CRISPR genome editing technologies to generate knock-out or knock-in lines for repair or introduction of mutations.

    Details about the genome editing services can be found here.

  • Induced pluripotent cell line derivation

    -We offer three non-integrating technologies (Sendai virus, miRNA and modified mRNA, and episomal vector) for reprogramming of a variety of somatic cell types.

    Details about the cell derivation service can be found here

  • Stem Cell Distribution

    -The iPS Core serves as a repository for Harvard hESC lines and both control and disease-specific hiPS cell lines.


Departmental Web Link(s):

Last updated: 2012-07-20T10:34:27.044-05:00