A searchable database of core laboratory facilities. Core Facilities

Center for Macromolecular Interactions (HMS)

Director: Arnett, Kelly L., Ph.D.

Location: Harvard Medical School, 240 Longwood Avenue, Building C, room 303, Boston, MA 02115

Core Summary:

The Center for Macromolecular Interactions (CMI), is a biophysical instrumentation facility for the characterization of macromolecules and their interactions. The CMI mission is to enhance basic research in the HMS community by providing scientific consultation, training and access to shared biophysical equipment. The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), and Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS).

Institutions:
  • Harvard Medical School
Personnel/Contact Information:

Director: Arnett, Kelly L., Ph.D.
Phone: (617) 432-5004
Email

Member: General Inquiries
Email

Facilities and Equipment:

Location of Core: Harvard Medical School, 240 Longwood Avenue, Building C, room 303, Boston, MA 02115

Major Equipment:

  • Biolayer Interferometry (BLI): ForteBio BLItz
  • Biolayer Interferometry (BLI): ForteBio Octet RED384
  • Circular Dichroism (CD): Jasco J815 Spectropolarimeter
  • Differential Scanning Fluorimetry (DSF): Life Technologies Quant Studio 6
  • Isothermal Titration Calorimetry (ITC): Microcal ITC200
  • MicroScale Thermophoresis (MST): NanoTemper Technologies Monolith NT.115pico
  • Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS): Agilent analytical SEC system
  • Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS): Wyatt MALS, QELS, and RI detectors
  • Surface Plasmon Resonance (SPR): GE Biacore T200
Services:
  • CMI Instrument Access

  • CMI Instrument Training


Departmental Web Link(s):

Last updated: 2017-05-30T13:36:31.293-05:00