A searchable database of core laboratory facilities. Core Facilities

Harvard Center for Biological Imaging (FAS)

Director: Richardson, Doug, Ph.D.

Location: Biological Labs, Room 2052, 16 Divinity Ave., Cambridge, MA 02138

Core Summary:

The Harvard Center for Biological Imaging (HCBI) was created to foster collaborative research in the most state-of-the-art facility available. To do this, a unique partnership with Carl Zeiss Microscopy has been established in which microscopy systems are replaced every 2-3 years, ensuring access to only the most up-to-date imaging systems. The facility is open 24 hours/day, 7 days/week and access to the HCBI is open to all academic and industrial researchers.

  • Harvard Faculty of Arts and Sciences
Personnel/Contact Information:

Director: Richardson, Doug, Ph.D.
Phone: (617) 496-5422

PI: Lichtman, Jeff, M.D., Ph.D.
Role: Jeremy R. Knowles Professor of Molecular and Cellular Biology
Phone: (617) 496-8943

Facilities and Equipment:

Location of Core: Biological Labs, Room 2052, 16 Divinity Ave., Cambridge, MA 02138

Major Equipment:

  • Graphic Processing Computers running Arivis, Imaris, Volocity, and ImageJ software packages
  • Logos Biosystems X-CLARITY tissue clearing device
  • Specialized Tissue Clearing Objectives (20x/1.0, WD=5.5mm) for Lightsheet and confocal
  • Zeiss AxioScan slidescanner with 100 slide capacity (brightfield or fluorescence)
  • Zeiss AxioZoom Motorized Fluorescence Zoom Microscope
  • Zeiss Cell Observer Live Cell Imaging System with Incubation, high-speed sCMOS and high-sensitivity back-thinned EMCCD Cameras
  • Zeiss Elyra Super-Resolution Microscope (SR-SIM and PALM/dSTORM)
  • Zeiss Lightsheet Z.1
  • Zeiss LSM 510 Inverted Confocal
  • Zeiss LSM 510 Upright Confocal
  • Zeiss LSM 5 Pascal Inverted Laser Scanning Confocal Microscope
  • Zeiss LSM 700 Confocal Microscope
  • Zeiss LSM 880 Confocal Inverted Microscope
  • Zeiss LSM 880 Confocal Upright Microscope
  • Zeiss LSM 880 NLO (For 2-Photon, SHG, etc.)
  • Zeiss LSM 880 with Airyscan and Incubation
  • Zeiss PALM Laser Capture Microdissection Microscope
  • Training service

    Service includes individual training on the instruments.

  • Use of instruments service

    Open to all academic and commercial researchers on an hourly rate basis. See HCBI website for details.

Departmental Web Link(s):

Last updated: 2017-03-29T08:47:54.504-05:00