A searchable database of core laboratory facilities. Core Facilities

High-Throughput Polymorphism Detection Core (DF/HCC)

Director: de Vivo, Immaculata, M.P.H., Ph.D.

Location: A Unit of the Partners HealthCare Center for Personalized Genetic Medicine Facility, PCPGM, NRB 164, 77 Avenue Louis Pasteur, Boston, MA 02115

Core Summary:

The mission of the High-Throughput Polymorphism Detection Core is to provide services to investigators conducting molecular analyses of somatic DNA collected as part of a wide range of investigations. This Core provides high-throughput assays of specific gene mutations and polymorphisms (SNPs) in the many situations where previously defined specific nucleotide alterations are of interest.

Institutions:
  • Dana-Farber/Harvard Cancer Center
Personnel/Contact Information:

Director: de Vivo, Immaculata, M.P.H., Ph.D.
Phone: (617) 432-1642
Email

Member: Blau, Ashley, MA
Phone: (617) 768-8557
Email

Member: General Inquiries
Email

Facilities and Equipment:

Location of Core: A Unit of the Partners HealthCare Center for Personalized Genetic Medicine Facility, PCPGM, NRB 164, 77 Avenue Louis Pasteur, Boston, MA 02115

Major Equipment:

  • ABI PRISM 7900HT sequence detection system
  • Beckman Coulter Biomek FX laboratory automation workstation
  • Deerac Fluidics Equator nanopipetter
  • Illumina iSCAN reader and Autoloader 2.0
  • Perkin Elmer Janus liquid Handler
  • Tecan Freedom EVO 150 liquid handler
Services:
  • Custom Illumina GoldenGate genotyping

  • Genotyping service using Illumina GoldenGate and Infinium technologies

  • Illumina Genotyping

  • Illumina Infinium genotyping

  • Illumina methylation analysis

  • SNP Analysis using OpenArray Genotyping

  • SNP Analysis using Taqman

  • Whole genome amplification service


Departmental Web Link(s):

Last updated: 2013-07-15T18:08:58.854-05:00