A searchable database of core laboratory facilities. Core Facilities

High-Throughput Polymorphism Detection Core (DF/HCC)

Director: de Vivo, Immaculata, M.P.H., Ph.D.

Location: Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Bldg 2. Room 255, Boston MA 02115

Core Summary:

The mission of the High-Throughput Polymorphism Detection Core is to provide services to investigators conducting molecular analyses of somatic DNA collected as part of a wide range of investigations. This Core provides high-throughput assays of specific gene mutations and polymorphisms (SNPs) in the many situations where previously defined specific nucleotide alterations are of interest.

Institutions:
  • Dana-Farber/Harvard Cancer Center
Personnel/Contact Information:

Director: de Vivo, Immaculata, M.P.H., Ph.D.
Phone: (617) 432-1642
Email

Member: Blau, Ashley, MA
Phone: (617) 768-8557
Email

Member: General Inquiries
Email

Facilities and Equipment:

Location of Core: Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Bldg 2. Room 255, Boston MA 02115

Major Equipment:

  • ABI PRISM 7900HT sequence detection system
  • Beckman Coulter Biomek FX laboratory automation workstation
  • Deerac Fluidics Equator nanopipetter
  • Illumina iSCAN reader and Autoloader 2.0
  • Ion Torrent PGM
  • OpenArray
  • Perkin Elmer Janus liquid Handler
  • Tecan Freedom EVO 150 liquid handler
Services:
  • Custom Illumina GoldenGate genotyping

  • Illumina Genotyping

  • Illumina Infinium genotyping

  • Illumina methylation analysis

  • Ion Torrent Targeted Sequencing

  • SNP Analysis using OpenArray Genotyping

  • SNP Analysis using Taqman

  • Telomere Length Analysis

  • Whole genome amplification service


Departmental Web Link(s):

Last updated: 2015-01-21T11:26:07.703-06:00