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DF/HCC Monoclonal Antibody Core

Director: Greenfield, Edward A.

Location: Dana-Farber Cancer Institute, 21/27 Burlington Ave, 4th Floor, Boston, MA 02215

Core Summary:

The mission of the DF/HCC Monoclonal Antibody Core (MAC) is to produce novel monoclonal antibodies that are directed against antigens of interest to Dana-Farber, the Harvard Cancer Center, and affiliated investigators. These monoclonal antibodies may be useful for basic research, drug discovery and clinical applications including diagnosis, surrogate markers for disease status, response to therapy or drug toxicity.

Given the diverse research needs of investigators at DFCI and the Harvard Community, the MAC should strive to support a wide range of antibody requests. A key component of the DF/HCC MAC is the ability to explore and develop new technologies that facilitate generation of monoclonal antibodies. The DF/HCC MAC should be capable of supporting all basic functions of generating, screening, storing and producing monoclonal antibodies.

  • Dana-Farber/Harvard Cancer Center
  • Dana-Farber Cancer Institute
Personnel/Contact Information:

Director: Greenfield, Edward A.
Phone: (617) 632-2209

Member: Nong, Yuhua
Role: Research Scientist
Phone: (617) 582-9152

PI: DeCaprio, James, M.D.
Role: Faculty Advisor
Phone: (617) 582-8601

Member: Brahmandam, Mohan
Role: Research Scientist
Phone: (617) 582-7143

Member: Bencsics, Craig
Role: Research Scientist
Phone: (617) 582-8035

Member: General Inquiries

  • Cryopreservation service

  • ELISA service

  • Endotoxin service

  • Flow cytometry service

  • Hybridoma fusion

  • Hybridoma productivity assay service

  • Isotyping service

  • Mycoplasma testing

  • Production and purification service

  • Protein development/cloning

  • RIMMS Rapid 21-day Rodent Immunization Service

  • Standard 68-day Rodent Immunization Service

  • Subcloning package service

  • Western blot service

Departmental Web Link(s):

Last updated: 2013-05-09T09:08:04.180-05:00